SliceIt is a genome-wide database of predicted sgRNAs based on CRISPR/Cas9 system to enable the systematic design of both low (gene or binding site centric) and high-throughput (genome-wide) CRISPR screens to understand the impact of editing the RNA-Binding Proteins’ binding sites in the human genome. SliceIt is powered by IGV JS genome browser for seamless data visualization and elastic search in the backend for efficient data storage and retrieval.